Questions about cognitive enhancers for people with mild impairment

30 Mar

Cholinesterase inhibitors and memantine are often used to treat dementia and mild cognitive impairment. Questions continue to be raised about the efficacy and safety of these drugs.

Here is a recent paper, published in The Canadian Medical Association Journal titled, “Efficacy and safety of cognitive enhancers for patients with mild cognitive impairment: a systematic review and meta-analysis.” It concludes:

“Cognitive enhancers did not improve cognition or function among patients with mild cognitive impairment and were associated with a greater risk of gastrointestinal harms. Our findings do not support the use of cognitive enhancers for mild cognitive impairment.”


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