Cholinesterase inhibitors and memantine are often used to treat dementia and mild cognitive impairment. Questions continue to be raised about the efficacy and safety of these drugs.
Here is a recent paper, published in The Canadian Medical Association Journal titled, “Efficacy and safety of cognitive enhancers for patients with mild cognitive impairment: a systematic review and meta-analysis.” It concludes:
“Cognitive enhancers did not improve cognition or function among patients with mild cognitive impairment and were associated with a greater risk of gastrointestinal harms. Our findings do not support the use of cognitive enhancers for mild cognitive impairment.”
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