Fraud fells Alzheimer’s “made to order” neurons paper in Cell

12 Apr

A widely cited Alzheimer’s paper is retracted.

Retraction Watch

cell414 In 2011, a group of researchers at Columbia University reported in Cell that they had been able to convert skin cells from patients with Alzheimer’s disease into functioning neurons — a finding that raised the exciting prospect of “ made to order ” brain cells for patients with the degenerative disease. As one researcher not involved with the study, led by  Asa Abeliovich , put it:

“[This is] simply a remarkable and complete piece of work which will now set a standard for stem cell work in neurological disease. The standard of the characterization of the neuronal cultures is very high,” John Hardy at University College London, U.K., wrote to [Alzforum]. He was not involved in the work but is taking a similar approach in his own lab.

According to the abstract of “Directed Conversion of Alzheimer’s Disease Patient Skin Fibroblasts into Functional Neurons:”

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