Psychiatric Disorders and Brain pH

27 Oct

From Scientific American:

There were earlier hints of the acid-disorder link: studies that directly measured pH—a metric of how acidic or basic something is—in dozens of postmortem human brains revealed lower pH (higher acidity) in patients with schizophrenia and bipolar disorder. Multiple studies in the past few decades have found that when people with panic disorder are exposed to air with a higher than normal concentration of carbon dioxide—which can combine with water in the body to form carbonic acid—they are more likely to experience panic attacks than healthy individuals are. Other research has revealed that the brains of people with panic disorder produce elevated levels of lactate, an acidic source of fuel that is constantly generated and consumed in the energy-hungry brain.

If these findings hold up, there may be new avenues for treatment.

 

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