The most recent issue of Clinical Psychological Science includes a paper titled “Effect of Micronutrients on Insomnia in Adults.” Here is the abstract:
Insomnia is a debilitating condition causing psychological distress and frequently comorbid with other mental health conditions. This study examined the effect of 8 weeks of treatment by broad spectrum micronutrients (vitamins and minerals) on insomnia using a multiple-baseline-across-participants open-label trial design. Seventeen adults were randomized to 1-, 2-, or 3-week baseline periods (14 completed). Self-report measures were the Consensus Sleep Diary–Morning (CSD-M), the Pittsburgh Insomnia Rating Scale (PIRS), and the Depression, Anxiety, Stress Scale (DASS). Baselines were generally stable. Treatment completers reported reliable and clinically significant change in insomnia severity (PIRS), in depression, stress, and anxiety (DASS), and on at least two aspects of sleep measured by the CDS-M. All completers were treatment-compliant, and side effects were minimal. Nutritional supplementation is shown to be a novel, beneficial treatment for insomnia in adults. Follow-up research using placebo-controlled designs as well as comparisons to cognitive-behavioral and other treatments is recommended.
I think the paper is quite interesting and it is consistent with some other research. I do, however, have some concerns. The researchers use a commercial brand name supplement, DSD (Daily Self Defense). Here is their description:
DSD contains all the B vitamins identified as being important for stress reduction (Table S1 in the Supplemental Material available online provides a full list of ingredients).
As a subscriber, I have access to the supplementary material, yet when I checked s1 it did not contain that information. I found a list of ingredients on line and I think the researchers should be clearer about why they thought this formulation would be more effective than other commercially available products. The main ingredients are very similar to what you would find in many commercially available multiple vitamin pills, plus 460 milligrams of a proprietary herbal blend.