Tag Archives: Body mass index

The chronobiology of dieting

14 Feb

When you eat may affect how much weight you gain. This article in The New York Times describes the research:

“Scientists, like mothers, have long suspected that midnight snacking is inadvisable. But until a few years ago, there was little in the way of science behind those suspicions. Now, a new study shows that mice prevented from eating at all hours avoided obesity and metabolic problems — even if their diet was sometimes unhealthful.”

You can see the research paper here. From the paper’s highlights:

“•Time-restricted feeding (TRF) confines food access to 9–12 hr during the active phase
•TRF is a therapeutic intervention against obesity without calorie restriction
•TRF protects against metabolic diseases even when briefly interrupted on weekends
•TRF is effective against high-fat, high-fructose, and high-sucrose diets”


Obesity and executive dysfunction

9 Apr

I recently came across this 2007 paper titled: “Elevated body mass index is associated with executive dysfunction in otherwise healthy adults.” Here is the abstract:

“There is growing evidence that obesity is linked to adverse neurocognitive outcome, including reduced cognitive functioning and Alzheimer disease. However, no study to date has determined whether the relationship between body mass index (BMI) and cognitive performance varies as a function of age. We examined attention and executive function in a cross-section of 408 healthy persons across the adult life span (20-82 years). Bivariate correlation showed that BMI was inversely related to performance on all cognitive tests. After controlling for possible confounding factors, overweight and obese adults (BMI > 25) exhibited poorer executive function test performance than normal weight adults (BMI, 18.5-24.9). No differences emerged in attention test performance, and there was no evidence of a BMI × age interaction for either cognitive domain. These results provide further evidence for the relationship between elevated BMI and reduced cognitive performance and suggest that this relationship does not vary with age. Further research is needed to identify the etiology of these deficits and whether they resolve after weight loss.”

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