Tag Archives: Folic acid

B vitamin treatment reduces Alzheimer’s related brain atrophy

22 Aug

A study published in The Proceedings of the National Academy of Sciences  reports that supplementation with B vitamins, specifically 0.8 mg of folic acid, 20 mg of vitamin B6 and .5 mg of vitamin B12, slowed cognitive decline and brain atrophy in individuals with Alzheimer’s disease. The pdf of the original paper can be found here.

The study appears to have been well conducted using a placebo control group. The authors believe that B vitamins reduce the body’s level of homocysteine, an amino acid that is linked to inflammation. According to the abstract:

“Our results show that B-vitamin supplementation can slow the atrophy of specific brain regions that are a key component of the AD (Alzheimer’s disease) process and that are associated with cognitive decline. Further B-vitamin supplementation trials focusing on elderly subjects with high homocysteine levels are warranted to see if progression to dementia can be prevented.”




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